Category Archives: Medicine

Roots of brutality

ns_logoWHY would an apparently normal young adult drop out of college and turn up some time later in a video performing a cold-blooded execution in the name of jihad? It’s a conundrum we have been forced to ponder ever since a group calling itself ISIS declared war on infidels. But 70 years ago we were asking something similar of guards in Nazi concentration camps – and, sadly, there have been plenty of opportunities to ponder the matter in between…

This article first appeared in New Scientist on 14 November 2015. To continue reading, click here (paywall).

A Faustian bargain

economist-logoHUNTINGTON’S disease is awful. It slowly robs its victims of mobility, wits and emotions. And there is no cure. The idea that it might be the obverse of something good sounds, to say the least, counter-intuitive. Yet that is the contention of a small band of neuroscientists who have been studying it. They suggest the underlying cause of Huntington’s, a strange form of genetic mutation called a triplet-repeat expansion, might also be one of the driving forces behind the expansion of the human brain. Huntington’s, these people suspect, may be a price humanity pays for being clever…

This article first appeared in The Economist on 7 March 2015. To continue reading, click here.

 

Funny feet

ns_logoMY RUNNING shoes have a thick sole and cushioned heel. I bought them five years ago, before the “barefoot” craze for minimalist shoes that would allow people to better emulate how our ancestors ran. Soon after that, reports began appearing of injuries sustained by runners who had adopted these shoes, and lawsuits were filed against some manufacturers. Now the maximally cushioned or “fat” shoe is back in vogue, and suddenly my old shoes look high-tech again…

This article first appeared in New Scientist on 24 January 2015. To continue reading, click here (paywall).

The forgetting gene

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ONE day in 1991, neurologist Warren Strittmatter asked his boss to look at some bewildering data. Strittmatter was studying amyloid-β, the main component of the molecular clumps found in the brains of people with Alzheimer’s disease. He was hunting for amyloid-binding proteins in the fluid that buffers the brain and spinal cord, and had fished out one called apolipoprotein E (ApoE), which had no obvious connection with the disease…

This article was inspired by an Ernst Strüngmann forum on brain diseases in March 2014 and first published in Nature on 6 June 2014. To continue reading, click here.